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t(14;18)-negative Follicular Lymphomas Are Associated with a High Frequency of BCL6 Rearrangement at the Alternative Breakpoint Region
A frequent chromosomal translocation in mature B-cell non-Hodgkin lymphoma affects band 3q27 and results in deregulation of the B-cell lymphoma 6 (BCL6) gene. Two breakpoint clusters have been described thus far, the major breakpoint region (MBR) and an alternative breakpoint region (ABR) that is lo...
Autores principales: | Gu, Keni, Fu, Kai, Jain, Smrati, Liu, Zhongfen, Iqbal, Javeed, Li, Min, Sanger, Warren G, Weisenburger, Dennis D, Greiner, Timothy C, Aoun, Patricia, Dave, Bhavana J, Chan, Wing C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736319/ https://www.ncbi.nlm.nih.gov/pubmed/19465899 http://dx.doi.org/10.1038/modpathol.2009.81 |
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