Can modular analysis identify disease-associated candidate genes for therapeutics?

Complex diseases such as allergy change gene expression in several cell types and tissues. Benson and colleagues have now shown, in a paper in BMC Systems Biology, that this complexity can be studied effectively using an integrated experimental and computational modular analysis. Their strategy reve...

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Detalles Bibliográficos
Autor principal: Tegnér, Jesper
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736663/
https://www.ncbi.nlm.nih.gov/pubmed/19519937
http://dx.doi.org/10.1186/jbiol149
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author Tegnér, Jesper
author_facet Tegnér, Jesper
author_sort Tegnér, Jesper
collection PubMed
description Complex diseases such as allergy change gene expression in several cell types and tissues. Benson and colleagues have now shown, in a paper in BMC Systems Biology, that this complexity can be studied effectively using an integrated experimental and computational modular analysis. Their strategy revealed a core of allergy-associated genes of potential therapeutic value.
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spelling pubmed-27366632009-11-28 Can modular analysis identify disease-associated candidate genes for therapeutics? Tegnér, Jesper J Biol Minireview Complex diseases such as allergy change gene expression in several cell types and tissues. Benson and colleagues have now shown, in a paper in BMC Systems Biology, that this complexity can be studied effectively using an integrated experimental and computational modular analysis. Their strategy revealed a core of allergy-associated genes of potential therapeutic value. BioMed Central 2009 2009-05-28 /pmc/articles/PMC2736663/ /pubmed/19519937 http://dx.doi.org/10.1186/jbiol149 Text en Copyright © 2009 BioMed Central Ltd
spellingShingle Minireview
Tegnér, Jesper
Can modular analysis identify disease-associated candidate genes for therapeutics?
title Can modular analysis identify disease-associated candidate genes for therapeutics?
title_full Can modular analysis identify disease-associated candidate genes for therapeutics?
title_fullStr Can modular analysis identify disease-associated candidate genes for therapeutics?
title_full_unstemmed Can modular analysis identify disease-associated candidate genes for therapeutics?
title_short Can modular analysis identify disease-associated candidate genes for therapeutics?
title_sort can modular analysis identify disease-associated candidate genes for therapeutics?
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736663/
https://www.ncbi.nlm.nih.gov/pubmed/19519937
http://dx.doi.org/10.1186/jbiol149
work_keys_str_mv AT tegnerjesper canmodularanalysisidentifydiseaseassociatedcandidategenesfortherapeutics

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