Parasite immunomodulation and polymorphisms of the immune system

Parasites are accomplished evaders of host immunity. Their evasion strategies have shaped every facet of the immune system, driving diversity within gene families and immune gene polymorphisms within populations. New studies published recently in BMC Biology and Journal of Experimental Medicine docu...

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Detalles Bibliográficos
Autor principal: Maizels, Rick M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736671/
https://www.ncbi.nlm.nih.gov/pubmed/19664200
http://dx.doi.org/10.1186/jbiol166
Descripción
Sumario:Parasites are accomplished evaders of host immunity. Their evasion strategies have shaped every facet of the immune system, driving diversity within gene families and immune gene polymorphisms within populations. New studies published recently in BMC Biology and Journal of Experimental Medicine document parasite-associated immunosuppression in natural populations and suggest that host genetic variants favoring resistance to parasites may be detrimental in the absence of infection.

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