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The role of apoptotic cell death in the radiosensitising effect of gemcitabine
BACKGROUND: The aim of this study was to evaluate the radiosensitising effect of gemcitabine, in terms of cell-cycle progression, induction of apoptosis, and to investigate the molecular events regulating apoptosis. METHODS: Tumour cells were treated with gemcitabine, radiation, or the combination....
Autores principales: | Pauwels, B, Vermorken, J B, Wouters, A, Ides, J, Van Laere, S, Lambrechts, H A J, Pattyn, G G O, Vermeulen, K, Meijnders, P, Lardon, F |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736812/ https://www.ncbi.nlm.nih.gov/pubmed/19672265 http://dx.doi.org/10.1038/sj.bjc.6605145 |
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