Oncogenic GNAQ mutations are not correlated with disease-free survival in uveal melanoma

BACKGROUND: Recently, oncogenic G protein alpha subunit q (GNAQ) mutations have been described in about 50% of uveal melanomas and in the blue nevi of the skin. METHODS: GNAQ exon 5 was amplified from 75 ciliary body and choroidal melanoma DNAs and sequenced directly. GNAQ mutation status was correl...

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Detalles Bibliográficos
Autores principales: Bauer, J, Kilic, E, Vaarwater, J, Bastian, B C, Garbe, C, de Klein, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736834/
https://www.ncbi.nlm.nih.gov/pubmed/19654573
http://dx.doi.org/10.1038/sj.bjc.6605226

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