Radioresistant cervical cancer shows upregulation of the NHEJ proteins DNA-PKcs, Ku70 and Ku86

BACKGROUND: Radiotherapy is central in the treatment of cervical cancer. The formation of DNA double-strand breaks is considered to be critical for the radiotherapeutic effect. The non-homologous end joining (NHEJ) proteins DNA–PKcs, Ku70 and Ku86 have a major role in repairing DNA lesions. The obje...

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Detalles Bibliográficos
Autores principales: Beskow, C, Skikuniene, J, Holgersson, Å, Nilsson, B, Lewensohn, R, Kanter, L, Viktorsson, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736845/
https://www.ncbi.nlm.nih.gov/pubmed/19672258
http://dx.doi.org/10.1038/sj.bjc.6605201

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