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Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery
BACKGROUND: To compare the clinical efficacy of lidocaine 2% with tetracaine 0.5% for cataract surgery. METHODS: In a randomized, multi-surgeon, controlled clinical trial,122 consecutive cataract cases eligible for topical anesthesia, were randomly assigned to receive lidocaine 2% gel (1 ml) or tetr...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736919/ https://www.ncbi.nlm.nih.gov/pubmed/19686592 http://dx.doi.org/10.1186/1471-2415-9-7 |
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author | Chalam, KV Murthy, Ravi K Agarwal, Swati Gupta, Shailesh K Grover, Sandeep |
author_facet | Chalam, KV Murthy, Ravi K Agarwal, Swati Gupta, Shailesh K Grover, Sandeep |
author_sort | Chalam, KV |
collection | PubMed |
description | BACKGROUND: To compare the clinical efficacy of lidocaine 2% with tetracaine 0.5% for cataract surgery. METHODS: In a randomized, multi-surgeon, controlled clinical trial,122 consecutive cataract cases eligible for topical anesthesia, were randomly assigned to receive lidocaine 2% gel (1 ml) or tetracaine solution 0.5% (TetraVisc, 0.5 ml) before clear corneal phacoemulsification. Main outcome measure was visual analog scale (0 to 10), which was used to measure intra-operative pain. Secondary outcome measures included patients' discomfort due to tissue manipulation and surgeon graded patients' cooperation. Duration of surgery and intra-operative complications were also recorded. RESULTS: The mean age in TetraVisc (TV) group was 70.4 years and in the lidocaine gel group (LG) it was 70.6 years (p = 0.89). Patient reported mean intra-operative pain scores by visual analog scale were 0.70 ± 0.31 in TV group and 1.8 ± 0.4 in LG group (P < 0.001). Mean patient cooperation was also marginally better in the TV group (8.3 ± 0.3) compared to LG group (8.4 ± 0.6) (P = 0.25). 96% of patients in TV group showed intra-operative corneal clarity compared to 91% in LG group. TV group had less (1 out of 61 patients, 1.6%) intra-operative complications than LG group (3 out of 61 patients, 4.8%). No anesthesia related complications were noted in either group CONCLUSION: Topical TetraVisc solution was superior to lidocaine 2% gel for pain control in patients undergoing clear corneal phacoemulsification. Lidocaine 2% gel is similar to TetraVisc in patient comfort and surgeon satisfaction. TRIAL REGISTRATION: Clinical trials number: ISRCTN78374774 |
format | Text |
id | pubmed-2736919 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-27369192009-09-03 Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery Chalam, KV Murthy, Ravi K Agarwal, Swati Gupta, Shailesh K Grover, Sandeep BMC Ophthalmol Research Article BACKGROUND: To compare the clinical efficacy of lidocaine 2% with tetracaine 0.5% for cataract surgery. METHODS: In a randomized, multi-surgeon, controlled clinical trial,122 consecutive cataract cases eligible for topical anesthesia, were randomly assigned to receive lidocaine 2% gel (1 ml) or tetracaine solution 0.5% (TetraVisc, 0.5 ml) before clear corneal phacoemulsification. Main outcome measure was visual analog scale (0 to 10), which was used to measure intra-operative pain. Secondary outcome measures included patients' discomfort due to tissue manipulation and surgeon graded patients' cooperation. Duration of surgery and intra-operative complications were also recorded. RESULTS: The mean age in TetraVisc (TV) group was 70.4 years and in the lidocaine gel group (LG) it was 70.6 years (p = 0.89). Patient reported mean intra-operative pain scores by visual analog scale were 0.70 ± 0.31 in TV group and 1.8 ± 0.4 in LG group (P < 0.001). Mean patient cooperation was also marginally better in the TV group (8.3 ± 0.3) compared to LG group (8.4 ± 0.6) (P = 0.25). 96% of patients in TV group showed intra-operative corneal clarity compared to 91% in LG group. TV group had less (1 out of 61 patients, 1.6%) intra-operative complications than LG group (3 out of 61 patients, 4.8%). No anesthesia related complications were noted in either group CONCLUSION: Topical TetraVisc solution was superior to lidocaine 2% gel for pain control in patients undergoing clear corneal phacoemulsification. Lidocaine 2% gel is similar to TetraVisc in patient comfort and surgeon satisfaction. TRIAL REGISTRATION: Clinical trials number: ISRCTN78374774 BioMed Central 2009-08-17 /pmc/articles/PMC2736919/ /pubmed/19686592 http://dx.doi.org/10.1186/1471-2415-9-7 Text en Copyright © 2009 Chalam et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Chalam, KV Murthy, Ravi K Agarwal, Swati Gupta, Shailesh K Grover, Sandeep Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery |
title | Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery |
title_full | Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery |
title_fullStr | Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery |
title_full_unstemmed | Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery |
title_short | Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery |
title_sort | comparative efficacy of topical tetravisc versus lidocaine gel in cataract surgery |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736919/ https://www.ncbi.nlm.nih.gov/pubmed/19686592 http://dx.doi.org/10.1186/1471-2415-9-7 |
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