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Rapid detection of the CYP2A6*12 hybrid allele by Pyrosequencing(® )technology
BACKGROUND: Identification of CYP2A6 alleles associated with reduced enzyme activity is important in the study of inter-individual differences in drug metabolism. CYP2A6*12 is a hybrid allele that results from unequal crossover between CYP2A6 and CYP2A7 genes. The 5' regulatory region and exons...
Autores principales: | Koontz, Deborah A, Huckins, Jacqueline J, Spencer, Antonina, Gallagher, Margaret L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736934/ https://www.ncbi.nlm.nih.gov/pubmed/19703308 http://dx.doi.org/10.1186/1471-2350-10-80 |
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