No Sib Pair Concordance for Breast or Ovarian Cancer in BRCA1 Mutation Carriers

Modifying factors might theoretically determine whether a BRCA1 mutation carrier contracts breast or ovarian cancer. If so, one would expect concordance for breast or ovarian cancer in affected sibships. We identified 64 pairs with cancers where one or both sisters were demonstrated to carry a BRCA1...

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Detalles Bibliográficos
Autores principales: Møller, Pål, Mæhle, Lovise, Clark, Neal, Apold, Jaran
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736994/
https://www.ncbi.nlm.nih.gov/pubmed/19725986
http://dx.doi.org/10.1186/1897-4287-5-2-67

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