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The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion
In humans, Streptococcus pneumoniae (SPN) is the leading cause of bacterial meningitis, a disease with high attributable mortality and frequent permanent neurological sequelae. The molecular mechanisms underlying the central nervous system tropism of SPN are incompletely understood, but include a pr...
Autores principales: | Uchiyama, Satoshi, Carlin, Aaron F., Khosravi, Arya, Weiman, Shannon, Banerjee, Anirban, Quach, Darin, Hightower, George, Mitchell, Tim J., Doran, Kelly S., Nizet, Victor |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737157/ https://www.ncbi.nlm.nih.gov/pubmed/19687228 http://dx.doi.org/10.1084/jem.20090386 |
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