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A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP

The innate immune system responds to unique molecular signatures that are widely conserved among microbes but that are not normally present in host cells. Compounds that stimulate innate immune pathways may be valuable in the design of novel adjuvants, vaccines, and other immunotherapeutics. The cyc...

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Detalles Bibliográficos
Autores principales:	McWhirter, Sarah M., Barbalat, Roman, Monroe, Kathryn M., Fontana, Mary F., Hyodo, Mamoru, Joncker, Nathalie T., Ishii, Ken J., Akira, Shizuo, Colonna, Marco, Chen, Zhijian J., Fitzgerald, Katherine A., Hayakawa, Yoshihiro, Vance, Russell E.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737161/ https://www.ncbi.nlm.nih.gov/pubmed/19652017 http://dx.doi.org/10.1084/jem.20082874

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