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Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

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The cause of Crohn's disease (CD) remains poorly understood. Counterintuitively, these patients possess an impaired acute inflammatory response, which could result in delayed clearance of bacteria penetrating the lining of the bowel and predispose to granuloma formation and chronicity. We teste...

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Detalles Bibliográficos
Autores principales:	Smith, Andrew M., Rahman, Farooq Z., Hayee, Bu'Hussain, Graham, Simon J., Marks, Daniel J.B., Sewell, Gavin W., Palmer, Christine D., Wilde, Jonathan, Foxwell, Brian M.J., Gloger, Israel S., Sweeting, Trevor, Marsh, Mark, Walker, Ann P., Bloom, Stuart L., Segal, Anthony W.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737162/ https://www.ncbi.nlm.nih.gov/pubmed/19652016 http://dx.doi.org/10.1084/jem.20091233

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