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Revisiting Crohn's disease as a primary immunodeficiency of macrophages
Despite two decades of mouse immunology and human genetics studies, the pathogenesis of Crohn's disease (CD) remains elusive. New clinical investigations suggest that CD may be caused by inborn errors of macrophages. These errors may result in impaired attraction of granulocytes to the gut wall...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737171/ https://www.ncbi.nlm.nih.gov/pubmed/19687225 http://dx.doi.org/10.1084/jem.20091683 |