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Interaction of Polysialic Acid with CCL21 Regulates the Migratory Capacity of Human Dendritic Cells
Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs). Immature DCs (iDCs) are situated in the periphery where they capture pathogen. Subsequently, they migrate as mature DCs (mDCs) to draining lymph nodes to activate T cells. CCR7 and CCL21 contribute to the migratory capacity o...
Autores principales: | Bax, Marieke, van Vliet, Sandra J., Litjens, Manja, García-Vallejo, Juan J., van Kooyk, Yvette |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737307/ https://www.ncbi.nlm.nih.gov/pubmed/19750015 http://dx.doi.org/10.1371/journal.pone.0006987 |
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