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Interaction of Polysialic Acid with CCL21 Regulates the Migratory Capacity of Human Dendritic Cells

Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs). Immature DCs (iDCs) are situated in the periphery where they capture pathogen. Subsequently, they migrate as mature DCs (mDCs) to draining lymph nodes to activate T cells. CCR7 and CCL21 contribute to the migratory capacity o...

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Detalles Bibliográficos
Autores principales: Bax, Marieke, van Vliet, Sandra J., Litjens, Manja, García-Vallejo, Juan J., van Kooyk, Yvette
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737307/
https://www.ncbi.nlm.nih.gov/pubmed/19750015
http://dx.doi.org/10.1371/journal.pone.0006987

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