Biphasic Myopathic Phenotype of Mouse DUX, an ORF within Conserved FSHD-Related Repeats

Facioscapulohumeral muscular dystrophy (FSHD) is caused by contractions of D4Z4 repeats at 4q35.2 thought to induce misregulation of nearby genes, one of which, DUX4, is actually localized within each repeat. A conserved ORF (mDUX), embedded within D4Z4-like repeats, encoding a double-homeodomain pr...

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Detalles Bibliográficos
Autores principales: Bosnakovski, Darko, Daughters, Randy S., Xu, Zhaohui, Slack, Jonathan M. W., Kyba, Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737622/
https://www.ncbi.nlm.nih.gov/pubmed/19756142
http://dx.doi.org/10.1371/journal.pone.0007003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737622/
https://www.ncbi.nlm.nih.gov/pubmed/19756142
http://dx.doi.org/10.1371/journal.pone.0007003

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