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Copper-Triggered Aggregation of Ubiquitin
Neurodegenerative disorders share common features comprising aggregation of misfolded proteins, failure of the ubiquitin-proteasome system, and increased levels of metal ions in the brain. Protein aggregates within affected cells often contain ubiquitin, however no report has focused on the aggregat...
Autores principales: | Arnesano, Fabio, Scintilla, Simone, Calò, Vincenza, Bonfrate, Elena, Ingrosso, Chiara, Losacco, Maurizio, Pellegrino, Teresa, Rizzarelli, Enrico, Natile, Giovanni |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737635/ https://www.ncbi.nlm.nih.gov/pubmed/19756145 http://dx.doi.org/10.1371/journal.pone.0007052 |
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