Pet Rodents and Fatal Lymphocytic Choriomeningitis in Transplant Patients

In April 2005, 4 transplant recipients became ill after receiving organs infected with lymphocytic choriomeningitis virus (LCMV); 3 subsequently died. All organs came from a donor who had been exposed to a hamster infected with LCMV. The hamster was traced back through a Rhode Island pet store to a...

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Detalles Bibliográficos
Autores principales: Amman, Brian R., Pavlin, Boris I., Albariño, Cesar G., Comer, James A., Erickson, Bobbie R., Oliver, Jennifer B., Sealy, Tara K., Vincent, Martin J., Nichol, Stuart T., Paddock, Christopher D., Tumpey, Abbigail J., Wagoner, Kent D., Glauer, R. David, Smith, Kathleen A., Winpisinger, Kim A., Parsely, Melody S., Wyrick, Phil, Hannafin, Christopher H., Bandy, Utpala, Zaki, Sherif, Rollin, Pierre E., Ksiazek, Thomas G.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738461/
https://www.ncbi.nlm.nih.gov/pubmed/17553250
http://dx.doi.org/10.3201/eid1305.061269
Descripción
Sumario:In April 2005, 4 transplant recipients became ill after receiving organs infected with lymphocytic choriomeningitis virus (LCMV); 3 subsequently died. All organs came from a donor who had been exposed to a hamster infected with LCMV. The hamster was traced back through a Rhode Island pet store to a distribution center in Ohio, and more LCMV-infected hamsters were discovered in both. Rodents from the Ohio facility and its parent facility in Arkansas were tested for the same LCMV strain as the 1 involved in the transplant-associated deaths. Phylogenetic analysis of virus sequences linked the rodents from the Ohio facility to the Rhode Island pet store, the index hamster, and the transplant recipients. This report details the animal traceback and the supporting laboratory investigations.

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