Dengue Hemorrhagic Fever in Infants: Research Opportunities Ignored

The age distribution of cases of dengue hemorrhagic fever and dengue shock syndrome (DHF/DSS) in infants under the age of 1 year are reported from Bangkok, Thailand, and for the first time for Ho Chi Minh City, Vietnam; Yangon, Myanmar; and Surabaya, Indonesia. The four dengue viruses were isolated...

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Detalles Bibliográficos
Autores principales: Halstead, Scott B., Lan, Nguyen Trong, Myint, Thein Thein, Shwe, Than Nu, Nisalak, Ananda, Kalyanarooj, Siripen, Nimmannitya, Suchitra, Soegijanto, Soegeng, Vaughn, David W., Endy, Timothy P.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2002
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738509/
https://www.ncbi.nlm.nih.gov/pubmed/12498666
http://dx.doi.org/10.3201/eid0812.020170
Descripción
Sumario:The age distribution of cases of dengue hemorrhagic fever and dengue shock syndrome (DHF/DSS) in infants under the age of 1 year are reported from Bangkok, Thailand, and for the first time for Ho Chi Minh City, Vietnam; Yangon, Myanmar; and Surabaya, Indonesia. The four dengue viruses were isolated from Thai infants, all of whom were having a primary dengue infection. Progress studying the immunologically distinct infant DHF/DSS has been limited; most contemporary research has centered on DHF/DSS accompanying secondary dengue infections. In designing research results obtained in studies on a congruent animal model, feline infectious peritonitis virus (FIPV) infections of kittens born to FIPV-immune queens should be considered. Research challenges presented by infant DHF/DSS are discussed.

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