Dengue Hemorrhagic Fever in Infants: Research Opportunities Ignored

The age distribution of cases of dengue hemorrhagic fever and dengue shock syndrome (DHF/DSS) in infants under the age of 1 year are reported from Bangkok, Thailand, and for the first time for Ho Chi Minh City, Vietnam; Yangon, Myanmar; and Surabaya, Indonesia. The four dengue viruses were isolated...

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Autores principales: Halstead, Scott B., Lan, Nguyen Trong, Myint, Thein Thein, Shwe, Than Nu, Nisalak, Ananda, Kalyanarooj, Siripen, Nimmannitya, Suchitra, Soegijanto, Soegeng, Vaughn, David W., Endy, Timothy P.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2002
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738509/
https://www.ncbi.nlm.nih.gov/pubmed/12498666
http://dx.doi.org/10.3201/eid0812.020170
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author Halstead, Scott B.
Lan, Nguyen Trong
Myint, Thein Thein
Shwe, Than Nu
Nisalak, Ananda
Kalyanarooj, Siripen
Nimmannitya, Suchitra
Soegijanto, Soegeng
Vaughn, David W.
Endy, Timothy P.
author_facet Halstead, Scott B.
Lan, Nguyen Trong
Myint, Thein Thein
Shwe, Than Nu
Nisalak, Ananda
Kalyanarooj, Siripen
Nimmannitya, Suchitra
Soegijanto, Soegeng
Vaughn, David W.
Endy, Timothy P.
author_sort Halstead, Scott B.
collection PubMed
description The age distribution of cases of dengue hemorrhagic fever and dengue shock syndrome (DHF/DSS) in infants under the age of 1 year are reported from Bangkok, Thailand, and for the first time for Ho Chi Minh City, Vietnam; Yangon, Myanmar; and Surabaya, Indonesia. The four dengue viruses were isolated from Thai infants, all of whom were having a primary dengue infection. Progress studying the immunologically distinct infant DHF/DSS has been limited; most contemporary research has centered on DHF/DSS accompanying secondary dengue infections. In designing research results obtained in studies on a congruent animal model, feline infectious peritonitis virus (FIPV) infections of kittens born to FIPV-immune queens should be considered. Research challenges presented by infant DHF/DSS are discussed.
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spelling pubmed-27385092009-09-16 Dengue Hemorrhagic Fever in Infants: Research Opportunities Ignored Halstead, Scott B. Lan, Nguyen Trong Myint, Thein Thein Shwe, Than Nu Nisalak, Ananda Kalyanarooj, Siripen Nimmannitya, Suchitra Soegijanto, Soegeng Vaughn, David W. Endy, Timothy P. Emerg Infect Dis Perspective The age distribution of cases of dengue hemorrhagic fever and dengue shock syndrome (DHF/DSS) in infants under the age of 1 year are reported from Bangkok, Thailand, and for the first time for Ho Chi Minh City, Vietnam; Yangon, Myanmar; and Surabaya, Indonesia. The four dengue viruses were isolated from Thai infants, all of whom were having a primary dengue infection. Progress studying the immunologically distinct infant DHF/DSS has been limited; most contemporary research has centered on DHF/DSS accompanying secondary dengue infections. In designing research results obtained in studies on a congruent animal model, feline infectious peritonitis virus (FIPV) infections of kittens born to FIPV-immune queens should be considered. Research challenges presented by infant DHF/DSS are discussed. Centers for Disease Control and Prevention 2002-12 /pmc/articles/PMC2738509/ /pubmed/12498666 http://dx.doi.org/10.3201/eid0812.020170 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Perspective
Halstead, Scott B.
Lan, Nguyen Trong
Myint, Thein Thein
Shwe, Than Nu
Nisalak, Ananda
Kalyanarooj, Siripen
Nimmannitya, Suchitra
Soegijanto, Soegeng
Vaughn, David W.
Endy, Timothy P.
Dengue Hemorrhagic Fever in Infants: Research Opportunities Ignored
title Dengue Hemorrhagic Fever in Infants: Research Opportunities Ignored
title_full Dengue Hemorrhagic Fever in Infants: Research Opportunities Ignored
title_fullStr Dengue Hemorrhagic Fever in Infants: Research Opportunities Ignored
title_full_unstemmed Dengue Hemorrhagic Fever in Infants: Research Opportunities Ignored
title_short Dengue Hemorrhagic Fever in Infants: Research Opportunities Ignored
title_sort dengue hemorrhagic fever in infants: research opportunities ignored
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738509/
https://www.ncbi.nlm.nih.gov/pubmed/12498666
http://dx.doi.org/10.3201/eid0812.020170
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