Impact of Genotyping of Mycobacterium tuberculosis on Public Health Practice in Massachusetts

Massachusetts was one of seven sentinel surveillance sites in the National Tuberculosis Genotyping and Surveillance Network. From 1996 through 2000, isolates from new patients with tuberculosis (TB) underwent genotyping. We describe the impact that genotyping had on public health practice in Massach...

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Detalles Bibliográficos
Autores principales: Miller, Ann C., Sharnprapai, Sharon, Suruki, Robert, Corkren, Edward, Nardell, Edward A., Driscoll, Jeffrey R., McGarry, Michael, Taber, Harry, Etkind, Sue
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2002
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738536/
https://www.ncbi.nlm.nih.gov/pubmed/12453357
http://dx.doi.org/10.3201/eid0811.020316
Descripción
Sumario:Massachusetts was one of seven sentinel surveillance sites in the National Tuberculosis Genotyping and Surveillance Network. From 1996 through 2000, isolates from new patients with tuberculosis (TB) underwent genotyping. We describe the impact that genotyping had on public health practice in Massachusetts and some limitations of the technique. Through genotyping, we explored the dynamics of TB outbreaks, investigated laboratory cross-contamination, and identified Mycobacterium tuberculosis strains, transmission sites, and accurate epidemiologic links. Genotyping should be used with epidemiologic follow-up to identify how resources can best be allocated to investigate genotypic findings.

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