Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns

Molecular epidemiologic studies provide evidence of transmission of Mycobacterium tuberculosis within clusters of patients whose isolates share identical IS6110-DNA fingerprint patterns. However, M. tuberculosis transmission among patients whose isolates have similar but not identical DNA fingerprin...

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Detalles Bibliográficos
Autores principales: Ijaz, Kashef, Yang, Zhenhua, Matthews, H. Stewart, Bates, Joseph H., Cave, M. Donald
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2002
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738543/
https://www.ncbi.nlm.nih.gov/pubmed/12453352
http://dx.doi.org/10.3201/eid0811.020284
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author Ijaz, Kashef
Yang, Zhenhua
Matthews, H. Stewart
Bates, Joseph H.
Cave, M. Donald
author_facet Ijaz, Kashef
Yang, Zhenhua
Matthews, H. Stewart
Bates, Joseph H.
Cave, M. Donald
author_sort Ijaz, Kashef
collection PubMed
description Molecular epidemiologic studies provide evidence of transmission of Mycobacterium tuberculosis within clusters of patients whose isolates share identical IS6110-DNA fingerprint patterns. However, M. tuberculosis transmission among patients whose isolates have similar but not identical DNA fingerprint patterns (i.e., differing by a single band) has not been well documented. We used DNA fingerprinting, combined with conventional epidemiology, to show unsuspected patterns of tuberculosis transmission associated with three public bars in the same city. Among clustered TB cases, DNA fingerprinting analysis of isolates with similar and identical fingerprints helped us discover epidemiologic links missed during routine tuberculosis contact investigations.
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spelling pubmed-27385432009-09-16 Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns Ijaz, Kashef Yang, Zhenhua Matthews, H. Stewart Bates, Joseph H. Cave, M. Donald Emerg Infect Dis Dispatch Molecular epidemiologic studies provide evidence of transmission of Mycobacterium tuberculosis within clusters of patients whose isolates share identical IS6110-DNA fingerprint patterns. However, M. tuberculosis transmission among patients whose isolates have similar but not identical DNA fingerprint patterns (i.e., differing by a single band) has not been well documented. We used DNA fingerprinting, combined with conventional epidemiology, to show unsuspected patterns of tuberculosis transmission associated with three public bars in the same city. Among clustered TB cases, DNA fingerprinting analysis of isolates with similar and identical fingerprints helped us discover epidemiologic links missed during routine tuberculosis contact investigations. Centers for Disease Control and Prevention 2002-11 /pmc/articles/PMC2738543/ /pubmed/12453352 http://dx.doi.org/10.3201/eid0811.020284 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Ijaz, Kashef
Yang, Zhenhua
Matthews, H. Stewart
Bates, Joseph H.
Cave, M. Donald
Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns
title Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns
title_full Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns
title_fullStr Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns
title_full_unstemmed Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns
title_short Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns
title_sort mycobacterium tuberculosis transmission between cluster members with similar fingerprint patterns
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738543/
https://www.ncbi.nlm.nih.gov/pubmed/12453352
http://dx.doi.org/10.3201/eid0811.020284
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AT batesjosephh mycobacteriumtuberculosistransmissionbetweenclustermemberswithsimilarfingerprintpatterns
AT cavemdonald mycobacteriumtuberculosistransmissionbetweenclustermemberswithsimilarfingerprintpatterns

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