Skin-Test Screening and Tuberculosis Transmission among the Homeless

We describe the implementation of a mandatory tuberculosis (TB) screening program that uses symptom screening and tuberculin skin testing in homeless shelters. We used the results of DNA fingerprinting of Mycobacterium tuberculosis isolates to evaluate the effect of the program on TB incidence and t...

Descripción completa

Detalles Bibliográficos
Autores principales: Kong, Po-Marn, Tapy, Jan, Calixto, Patricia, Burman, William J., Reves, Randall R., Yang, Zhenhua, Cave, M. Donald
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2002
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738560/
https://www.ncbi.nlm.nih.gov/pubmed/12453356
http://dx.doi.org/10.3201/eid0811.020306
_version_ 1782171526066339840
author Kong, Po-Marn
Tapy, Jan
Calixto, Patricia
Burman, William J.
Reves, Randall R.
Yang, Zhenhua
Cave, M. Donald
author_facet Kong, Po-Marn
Tapy, Jan
Calixto, Patricia
Burman, William J.
Reves, Randall R.
Yang, Zhenhua
Cave, M. Donald
author_sort Kong, Po-Marn
collection PubMed
description We describe the implementation of a mandatory tuberculosis (TB) screening program that uses symptom screening and tuberculin skin testing in homeless shelters. We used the results of DNA fingerprinting of Mycobacterium tuberculosis isolates to evaluate the effect of the program on TB incidence and transmission. After the program was implemented, the proportion of cases among homeless persons detected by screening activities increased, and the estimated TB incidence decreased from 510 to 121 cases per 100,000 population per year. Recent transmission, defined by DNA fingerprinting analysis as clustered patterns occurring within 2 years, decreased from 49% to 14% (p=0.03). Our results suggest that the shelter-based screening program decreased the incidence of TB by decreasing its transmission among the homeless.
format Text
id pubmed-2738560
institution National Center for Biotechnology Information
language English
publishDate 2002
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-27385602009-09-16 Skin-Test Screening and Tuberculosis Transmission among the Homeless Kong, Po-Marn Tapy, Jan Calixto, Patricia Burman, William J. Reves, Randall R. Yang, Zhenhua Cave, M. Donald Emerg Infect Dis Research We describe the implementation of a mandatory tuberculosis (TB) screening program that uses symptom screening and tuberculin skin testing in homeless shelters. We used the results of DNA fingerprinting of Mycobacterium tuberculosis isolates to evaluate the effect of the program on TB incidence and transmission. After the program was implemented, the proportion of cases among homeless persons detected by screening activities increased, and the estimated TB incidence decreased from 510 to 121 cases per 100,000 population per year. Recent transmission, defined by DNA fingerprinting analysis as clustered patterns occurring within 2 years, decreased from 49% to 14% (p=0.03). Our results suggest that the shelter-based screening program decreased the incidence of TB by decreasing its transmission among the homeless. Centers for Disease Control and Prevention 2002-11 /pmc/articles/PMC2738560/ /pubmed/12453356 http://dx.doi.org/10.3201/eid0811.020306 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Kong, Po-Marn
Tapy, Jan
Calixto, Patricia
Burman, William J.
Reves, Randall R.
Yang, Zhenhua
Cave, M. Donald
Skin-Test Screening and Tuberculosis Transmission among the Homeless
title Skin-Test Screening and Tuberculosis Transmission among the Homeless
title_full Skin-Test Screening and Tuberculosis Transmission among the Homeless
title_fullStr Skin-Test Screening and Tuberculosis Transmission among the Homeless
title_full_unstemmed Skin-Test Screening and Tuberculosis Transmission among the Homeless
title_short Skin-Test Screening and Tuberculosis Transmission among the Homeless
title_sort skin-test screening and tuberculosis transmission among the homeless
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738560/
https://www.ncbi.nlm.nih.gov/pubmed/12453356
http://dx.doi.org/10.3201/eid0811.020306
work_keys_str_mv AT kongpomarn skintestscreeningandtuberculosistransmissionamongthehomeless
AT tapyjan skintestscreeningandtuberculosistransmissionamongthehomeless
AT calixtopatricia skintestscreeningandtuberculosistransmissionamongthehomeless
AT burmanwilliamj skintestscreeningandtuberculosistransmissionamongthehomeless
AT revesrandallr skintestscreeningandtuberculosistransmissionamongthehomeless
AT yangzhenhua skintestscreeningandtuberculosistransmissionamongthehomeless
AT cavemdonald skintestscreeningandtuberculosistransmissionamongthehomeless

Ejemplares similares