Molecular Typing of Mycobacterium tuberculosis Strains with a Common Two-Band IS6110 Pattern

We conducted a population-based molecular typing of all Mycobacterium tuberculosis isolates obtained in Alabama since 1994. Of 2,452 isolates, 1,013 (41%) had fewer than 6 bands of IS6110; 348 (14%) had a single two-band pattern (JH2). With conventional epidemiologic methods, we identified three gro...

Descripción completa

Detalles Bibliográficos
Autores principales: Lok, Kerry H., Benjamin, William H., Kimerling, Michael E., Pruitt, Virginia, Mulcahy, Donna, Robinson, Nancy, Keenan, Nancy B., Dunlap, Nancy E.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2002
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738563/
https://www.ncbi.nlm.nih.gov/pubmed/12453360
http://dx.doi.org/10.3201/eid0811.020292
Descripción
Sumario:We conducted a population-based molecular typing of all Mycobacterium tuberculosis isolates obtained in Alabama since 1994. Of 2,452 isolates, 1,013 (41%) had fewer than 6 bands of IS6110; 348 (14%) had a single two-band pattern (JH2). With conventional epidemiologic methods, we identified three groups of related patients with JH2 isolates. Spoligotyping and pattern of variable number of tandem repeats identified 10 molecular groups; two found by conventional methods were subdivided.

Ejemplares similares