Molecular Typing of Mycobacterium tuberculosis Strains with a Common Two-Band IS6110 Pattern

We conducted a population-based molecular typing of all Mycobacterium tuberculosis isolates obtained in Alabama since 1994. Of 2,452 isolates, 1,013 (41%) had fewer than 6 bands of IS6110; 348 (14%) had a single two-band pattern (JH2). With conventional epidemiologic methods, we identified three gro...

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Detalles Bibliográficos
Autores principales: Lok, Kerry H., Benjamin, William H., Kimerling, Michael E., Pruitt, Virginia, Mulcahy, Donna, Robinson, Nancy, Keenan, Nancy B., Dunlap, Nancy E.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2002
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738563/
https://www.ncbi.nlm.nih.gov/pubmed/12453360
http://dx.doi.org/10.3201/eid0811.020292
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author Lok, Kerry H.
Benjamin, William H.
Kimerling, Michael E.
Pruitt, Virginia
Mulcahy, Donna
Robinson, Nancy
Keenan, Nancy B.
Dunlap, Nancy E.
author_facet Lok, Kerry H.
Benjamin, William H.
Kimerling, Michael E.
Pruitt, Virginia
Mulcahy, Donna
Robinson, Nancy
Keenan, Nancy B.
Dunlap, Nancy E.
author_sort Lok, Kerry H.
collection PubMed
description We conducted a population-based molecular typing of all Mycobacterium tuberculosis isolates obtained in Alabama since 1994. Of 2,452 isolates, 1,013 (41%) had fewer than 6 bands of IS6110; 348 (14%) had a single two-band pattern (JH2). With conventional epidemiologic methods, we identified three groups of related patients with JH2 isolates. Spoligotyping and pattern of variable number of tandem repeats identified 10 molecular groups; two found by conventional methods were subdivided.
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spelling pubmed-27385632009-09-16 Molecular Typing of Mycobacterium tuberculosis Strains with a Common Two-Band IS6110 Pattern Lok, Kerry H. Benjamin, William H. Kimerling, Michael E. Pruitt, Virginia Mulcahy, Donna Robinson, Nancy Keenan, Nancy B. Dunlap, Nancy E. Emerg Infect Dis Dispatch We conducted a population-based molecular typing of all Mycobacterium tuberculosis isolates obtained in Alabama since 1994. Of 2,452 isolates, 1,013 (41%) had fewer than 6 bands of IS6110; 348 (14%) had a single two-band pattern (JH2). With conventional epidemiologic methods, we identified three groups of related patients with JH2 isolates. Spoligotyping and pattern of variable number of tandem repeats identified 10 molecular groups; two found by conventional methods were subdivided. Centers for Disease Control and Prevention 2002-11 /pmc/articles/PMC2738563/ /pubmed/12453360 http://dx.doi.org/10.3201/eid0811.020292 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Lok, Kerry H.
Benjamin, William H.
Kimerling, Michael E.
Pruitt, Virginia
Mulcahy, Donna
Robinson, Nancy
Keenan, Nancy B.
Dunlap, Nancy E.
Molecular Typing of Mycobacterium tuberculosis Strains with a Common Two-Band IS6110 Pattern
title Molecular Typing of Mycobacterium tuberculosis Strains with a Common Two-Band IS6110 Pattern
title_full Molecular Typing of Mycobacterium tuberculosis Strains with a Common Two-Band IS6110 Pattern
title_fullStr Molecular Typing of Mycobacterium tuberculosis Strains with a Common Two-Band IS6110 Pattern
title_full_unstemmed Molecular Typing of Mycobacterium tuberculosis Strains with a Common Two-Band IS6110 Pattern
title_short Molecular Typing of Mycobacterium tuberculosis Strains with a Common Two-Band IS6110 Pattern
title_sort molecular typing of mycobacterium tuberculosis strains with a common two-band is6110 pattern
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738563/
https://www.ncbi.nlm.nih.gov/pubmed/12453360
http://dx.doi.org/10.3201/eid0811.020292
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