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Functional RET G691S Polymorphism in Cutaneous Malignant Melanoma

RET proto-oncogene encodes a receptor tyrosine kinase whose ligand is glial cell line-derived neurotrophic factor (GDNF), and its polymorphism at G691S juxtamembrane region (RETp) is a germline polymorphism. Cutaneous melanomas, particularly the desmoplastic subtype, are highly neurotropic; thus we...

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Detalles Bibliográficos
Autores principales:	Narita, N, Tanemura, A, Murali, R, Scolyer, RA, Huang, S, Arigami, T, Yanagita, S, Chong, KK, Thompson, JF, Morton, DL, Hoon, DS
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738597/ https://www.ncbi.nlm.nih.gov/pubmed/19561646 http://dx.doi.org/10.1038/onc.2009.164

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