Vesnarinone downregulates CXCR4 expression via upregulation of Krüppel-like factor 2 in oral cancer cells

BACKGROUND: We have demonstrated that the stromal cell-derived factor-1 (SDF-1; CXCL12)/CXCR4 system is involved in the establishment of lymph node metastasis in oral squamous cell carcinoma (SCC). Chemotherapy is a powerful tool for the treatment of oral cancer, including oral SCC; however, the eff...

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Detalles Bibliográficos
Autores principales: Uchida, Daisuke, Onoue, Tomitaro, Begum, Nasima-Mila, Kuribayashi, Nobuyuki, Tomizuka, Yoshifumi, Tamatani, Tetsuya, Nagai, Hirokazu, Miyamoto, Youji
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738650/
https://www.ncbi.nlm.nih.gov/pubmed/19671192
http://dx.doi.org/10.1186/1476-4598-8-62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738650/
https://www.ncbi.nlm.nih.gov/pubmed/19671192
http://dx.doi.org/10.1186/1476-4598-8-62

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