Wiskott–Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation

Regulation of the actin cytoskeleton is crucial for many aspects of correct and cooperative functioning of immune cells, such as migration, antigen uptake and cell activation. The Wiskott–Aldrich Syndrome protein (WASp) is an important regulator of actin cytoskeletal rearrangements and lack of this...

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Detalles Bibliográficos
Autores principales: Bouma, Gerben, Burns, Siobhan O., Thrasher, Adrian J.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738782/
https://www.ncbi.nlm.nih.gov/pubmed/19628299
http://dx.doi.org/10.1016/j.imbio.2009.06.009

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