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The Liver-Brain Axis of Alcohol-Mediated Neurodegeneration: Role of Toxic Lipids
Alcohol abuse causes progressive toxicity and degeneration in liver and brain due to insulin resistance, which exacerbates oxidative stress and pro-inflammatory cytokine activation. Alcohol-induced steatohepatitis promotes synthesis and accumulation of ceramides and other toxic lipids that cause ins...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Molecular Diversity Preservation International (MDPI)
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738898/ https://www.ncbi.nlm.nih.gov/pubmed/19742171 http://dx.doi.org/10.3390/ijerph6072055 |