Cargando…
The Liver-Brain Axis of Alcohol-Mediated Neurodegeneration: Role of Toxic Lipids
Alcohol abuse causes progressive toxicity and degeneration in liver and brain due to insulin resistance, which exacerbates oxidative stress and pro-inflammatory cytokine activation. Alcohol-induced steatohepatitis promotes synthesis and accumulation of ceramides and other toxic lipids that cause ins...
Autores principales: | de la Monte, Suzanne M., Longato, Lisa, Tong, Ming, DeNucci, Sarah, Wands, Jack R. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738898/ https://www.ncbi.nlm.nih.gov/pubmed/19742171 http://dx.doi.org/10.3390/ijerph6072055 |
Ejemplares similares
-
Rat Strain Differences in Susceptibility to Alcohol-Induced Chronic Liver Injury and Hepatic Insulin Resistance
por: DeNucci, Sarah M., et al.
Publicado: (2010) -
Nitrosamine exposure exacerbates high fat diet-mediated type 2 diabetes mellitus, non-alcoholic steatohepatitis, and neurodegeneration with cognitive impairment
por: de la Monte, Suzanne M, et al.
Publicado: (2009) -
Insulin Resistance, Ceramide Accumulation, and Endoplasmic Reticulum Stress in Human Chronic Alcohol-Related Liver Disease
por: Longato, Lisa, et al.
Publicado: (2012) -
Acetaldehyde adducts in alcoholic liver disease
por: Setshedi, Mashiko, et al.
Publicado: (2010) -
Early limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabetes and neurodegeneration
por: Tong, Ming, et al.
Publicado: (2010)