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Effect of Seven Newly Synthesized and Currently Available Oxime Cholinesterase Reactivators on Cyclosarin-Intoxicated Rats

Seven new oxime-based acetylcholinesterase reactivators were compared with three currently available ones (obidoxime, trimedoxime, HI-6) for their ability to lessen cholinesterase inhibition in blood and brain of cyclosarin-treated rats. Oximes were given at doses of 5% their LD(50) along with 21 mg...

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Detalles Bibliográficos
Autores principales:	Karasova, Jana Zdarova, Kassa, Jiri, Musilek, Kamil, Pohanka, Miroslav, Novotny, Ladislav, Kuca, Kamil
Formato:	Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738912/ https://www.ncbi.nlm.nih.gov/pubmed/19742125 http://dx.doi.org/10.3390/ijms10073065

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