A common haplotype within the PON1 promoter region is associated with sporadic ALS

Amyotrophic lateral sclerosis (ALS) is a progressive, neurodegenerative disorder of upper and lower motor neurons. Genetic variants in the paraoxonase gene cluster have been associated with susceptibility to sporadic ALS. Because these studies have yielded conflicting results, we have further invest...

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Detalles Bibliográficos
Autores principales: Landers, John E., Shi, Lijia, Cho, Ting-Jan, Glass, Jonathan D., Shaw, Christopher E., Leigh, P. Nigel, Diekstra, Frank, Polak, Meraida, Rodriguez-Leyva, Ildefonso, Niemann, Stephan, Traynor, Bryan J., Mckenna-Yasek, Diane, Sapp, Peter C., Al-Chalabi, Ammar, Wills, Anne-Marie A., Brown, Robert H.
Formato: Texto
Lenguaje:English
Publicado: Taylor & Francis 2008
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739087/
https://www.ncbi.nlm.nih.gov/pubmed/18618303
http://dx.doi.org/10.1080/17482960802233177

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