Cbl Negatively Regulates JNK Activation and Cell Death

Here, we explore the role of Cbl proteins in regulation of neuronal apoptosis. In two paradigms of neuron apoptosis – nerve growth factor (NGF) deprivation and DNA damage – cellular levels of c-Cbl and Cbl-b fell well before onset of death. NGF deprivation also induced rapid loss of tyrosine phospho...

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Detalles Bibliográficos
Autores principales: Sproul, Andrew A., Xu, Zhiheng, Wilhelm, Michael, Gire, Stephen, Greene, Lloyd A.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739106/
https://www.ncbi.nlm.nih.gov/pubmed/19546888
http://dx.doi.org/10.1038/cr.2009.74

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739106/
https://www.ncbi.nlm.nih.gov/pubmed/19546888
http://dx.doi.org/10.1038/cr.2009.74

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