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Cbl Negatively Regulates JNK Activation and Cell Death
Here, we explore the role of Cbl proteins in regulation of neuronal apoptosis. In two paradigms of neuron apoptosis – nerve growth factor (NGF) deprivation and DNA damage – cellular levels of c-Cbl and Cbl-b fell well before onset of death. NGF deprivation also induced rapid loss of tyrosine phospho...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739106/ https://www.ncbi.nlm.nih.gov/pubmed/19546888 http://dx.doi.org/10.1038/cr.2009.74 |