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Reduction of lipoxidative load by secretory phospholipase A2 inhibition protects against neurovascular injury following experimental stroke in rat

BACKGROUND: In animal models, ischemia reperfusion (IR) injury triggers membrane lipid degradation and accumulation of lipoxidative exacerbations in neurovascular unit, leading to blood brain barrier (BBB) damage and neurologic deficits. In this study, we investigated whether impeding membrane lipid...

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Detalles Bibliográficos
Autores principales:	Hoda, Md Nasrul, Singh, Inderjit, Singh, Avtar K, Khan, Mushfiquddin
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739168/ https://www.ncbi.nlm.nih.gov/pubmed/19678934 http://dx.doi.org/10.1186/1742-2094-6-21

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