Assessing the druggability of protein-protein interactions by a supervised machine-learning method

BACKGROUND: Protein-protein interactions (PPIs) are challenging but attractive targets of small molecule drugs for therapeutic interventions of human diseases. In this era of rapid accumulation of PPI data, there is great need for a methodology that can efficiently select drug target PPIs by holisti...

Descripción completa

Detalles Bibliográficos
Autores principales: Sugaya, Nobuyoshi, Ikeda, Kazuyoshi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739204/
https://www.ncbi.nlm.nih.gov/pubmed/19703312
http://dx.doi.org/10.1186/1471-2105-10-263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739204/
https://www.ncbi.nlm.nih.gov/pubmed/19703312
http://dx.doi.org/10.1186/1471-2105-10-263

Ejemplares similares