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Assessing the druggability of protein-protein interactions by a supervised machine-learning method
BACKGROUND: Protein-protein interactions (PPIs) are challenging but attractive targets of small molecule drugs for therapeutic interventions of human diseases. In this era of rapid accumulation of PPI data, there is great need for a methodology that can efficiently select drug target PPIs by holisti...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739204/ https://www.ncbi.nlm.nih.gov/pubmed/19703312 http://dx.doi.org/10.1186/1471-2105-10-263 |