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Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography

BACKGROUND: The lysosomal 66.3 kDa protein from mouse is a soluble, mannose 6-phosphate containing protein of so far unknown function. It is synthesized as a glycosylated 75 kDa precursor that undergoes limited proteolysis leading to a 28 kDa N- and a 40 kDa C-terminal fragment. RESULTS: In order to...

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Detalles Bibliográficos
Autores principales: Lakomek, Kristina, Dickmanns, Achim, Kettwig, Matthias, Urlaub, Henning, Ficner, Ralf, Lübke, Torben
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739207/
https://www.ncbi.nlm.nih.gov/pubmed/19706171
http://dx.doi.org/10.1186/1472-6807-9-56

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