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Apolipoprotein E4 (1–272) fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells

BACKGROUND: Apolipoprotein E allele ε4 (apoE4) is a strong risk factor for developing Alzheimer's disease (AD). Secreted apoE has a critical function in redistributing lipids among central nervous system cells to maintain normal lipid homeostasis. In addition, previous reports have shown that a...

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Detalles Bibliográficos
Autores principales:	Nakamura, Toshiyuki, Watanabe, Atsushi, Fujino, Takahiro, Hosono, Takashi, Michikawa, Makoto
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739857/ https://www.ncbi.nlm.nih.gov/pubmed/19695092 http://dx.doi.org/10.1186/1750-1326-4-35

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