Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers

BACKGROUND: Detoxification in the liver involves activation of nuclear receptors, such as the constitutive androstane receptor (CAR), which regulate downstream genes of xenobiotic metabolism. Frequently, the metabolism of endobiotics is also modulated, resulting in potentially harmful effects. We th...

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Detalles Bibliográficos
Autores principales: Režen, Tadeja, Tamasi, Viola, Lövgren-Sandblom, Anita, Björkhem, Ingemar, Meyer, Urs A, Rozman, Damjana
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739862/
https://www.ncbi.nlm.nih.gov/pubmed/19691840
http://dx.doi.org/10.1186/1471-2164-10-384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739862/
https://www.ncbi.nlm.nih.gov/pubmed/19691840
http://dx.doi.org/10.1186/1471-2164-10-384

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