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Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers
BACKGROUND: Detoxification in the liver involves activation of nuclear receptors, such as the constitutive androstane receptor (CAR), which regulate downstream genes of xenobiotic metabolism. Frequently, the metabolism of endobiotics is also modulated, resulting in potentially harmful effects. We th...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739862/ https://www.ncbi.nlm.nih.gov/pubmed/19691840 http://dx.doi.org/10.1186/1471-2164-10-384 |