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Synaptotagmin-1 functions as the Ca(2+)-sensor for spontaneous release
Spontaneous ‘mini’ release occurs at all synapses, but its nature remains enigmatic. Here, we show that in murine cortical neurons, >95% of spontaneous release is induced by Ca(2+)-binding to synaptotagmin-1, the Ca(2+)-sensor for fast synchronous neurotransmitter release. Thus, spontaneous and e...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739891/ https://www.ncbi.nlm.nih.gov/pubmed/19412166 http://dx.doi.org/10.1038/nn.2320 |