Topiramate induced acute transient myopia: a case report

INTRODUCTION: Topiramate is a sulfamate-substituted monosaccharide mainly used to treat epilepsy in children and adults and for prophylaxis of migraine. This article describes a case of topiramate induced acute transient myopia. The underlying mechanism and management is discussed. CASE PRESENTATION...

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Detalles Bibliográficos
Autor principal: Gawley, Sandra D
Formato: Texto
Lenguaje:English
Publicado: Cases Network Ltd 2009
Materias:
Case report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740198/
https://www.ncbi.nlm.nih.gov/pubmed/19829963
http://dx.doi.org/10.4076/1757-1626-2-7430
Descripción
Sumario:INTRODUCTION: Topiramate is a sulfamate-substituted monosaccharide mainly used to treat epilepsy in children and adults and for prophylaxis of migraine. This article describes a case of topiramate induced acute transient myopia. The underlying mechanism and management is discussed. CASE PRESENTATION: A 34-year-old female complained of sudden onset of blurred vision, 9 days prior to this she had commenced topiramate therapy for migraine prophylaxis. Visual acuity was reduced to 6/36 right eye and 2/60 left eye. Examination revealed ocular anatomical and myopic refractive changes which resolved quickly following discontinuation of the drug. CONCLUSION: Ophthalmologists need to be aware of the potential ocular side effects of topiramate. Although relatively rare prompt recognition is key so appropriate management can be instituted.

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