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Novel Mitochondrial Substrates of Omi Indicate a New Regulatory Role in Neurodegenerative Disorders
The mitochondrial protease OMI (also known as HtrA2) has been implicated in Parkinson's Disease (PD) and deletion or protease domain point mutations have shown profound neuropathologies in mice. A beneficial role by OMI, in preserving cell viability, is assumed to occur via the avoidance of dys...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740829/ https://www.ncbi.nlm.nih.gov/pubmed/19763263 http://dx.doi.org/10.1371/journal.pone.0007100 |