Loss of RhoB Expression Enhances the Myelodysplastic Phenotype of Mammalian Diaphanous-Related Formin mDia1 Knockout Mice

Myelodysplastic syndrome (MDS) is characterized by ineffective hematopoiesis and hyperplastic bone marrow. Complete loss or interstitial deletions of the long arm of chromosome 5 occur frequently in MDS. One candidate tumor suppressor on 5q is the mammalian Diaphanous (mDia)-related formin mDia1, en...

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Detalles Bibliográficos
Autores principales: DeWard, Aaron D., Leali, Kellie, West, Richard A., Prendergast, George C., Alberts, Arthur S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740832/
https://www.ncbi.nlm.nih.gov/pubmed/19768111
http://dx.doi.org/10.1371/journal.pone.0007102

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