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BRCA1 Interacts with Smad3 and Regulates Smad3-Mediated TGF-β Signaling during Oxidative Stress Responses

BACKGROUND: BRCA1 is a key regulatory protein participating in cell cycle checkpoint and DNA damage repair networks. BRCA1 plays important roles in protecting numerous cellular processes in response to cell damaging signals. Transforming growth factor-beta (TGF-β) is a potent regulator of growth, ap...

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Detalles Bibliográficos
Autores principales:	Li, Huchun, Sekine, Masayuki, Seng, Seyha, Avraham, Shalom, Avraham, Hava Karsenty
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740868/ https://www.ncbi.nlm.nih.gov/pubmed/19768112 http://dx.doi.org/10.1371/journal.pone.0007091

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