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Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2
Glucose intolerance in C57Bl/6 mice has been associated with mutations in the nicotinamide nucleotide transhydrogenase (Nnt) gene. It has been proposed that the absence of NNT from mitochondria leads to increased mitochondrial reactive oxygen species production and subsequent activation of uncouplin...
Autores principales: | Parker, Nadeene, Vidal-Puig, Antonio J., Azzu, Vian, Brand, Martin D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Pub. Co
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741566/ https://www.ncbi.nlm.nih.gov/pubmed/19539600 http://dx.doi.org/10.1016/j.bbabio.2009.06.005 |
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