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Genotype–phenotype interactions in primary dystonias revealed by differential changes in brain structure
Our understanding of how genotype determines phenotype in primary dystonia is limited. Familial young-onset primary dystonia is commonly due to the DYT1 gene mutation. A critical question, given the 30% penetrance of clinical symptoms in DYT1 mutation carriers, is why the same genotype leads to diff...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741581/ https://www.ncbi.nlm.nih.gov/pubmed/19344776 http://dx.doi.org/10.1016/j.neuroimage.2009.03.057 |