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Circadian and Social Cues Regulate Ion Channel Trafficking

Electric fish generate and sense electric fields for navigation and communication. These signals can be energetically costly to produce and can attract electroreceptive predators. To minimize costs, some nocturnally active electric fish rapidly boost the power of their signals only at times of high...

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Detalles Bibliográficos
Autores principales: Markham, Michael R., McAnelly, M. Lynne, Stoddard, Philip K., Zakon, Harold H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741594/
https://www.ncbi.nlm.nih.gov/pubmed/19787026
http://dx.doi.org/10.1371/journal.pbio.1000203
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author Markham, Michael R.
McAnelly, M. Lynne
Stoddard, Philip K.
Zakon, Harold H.
author_facet Markham, Michael R.
McAnelly, M. Lynne
Stoddard, Philip K.
Zakon, Harold H.
author_sort Markham, Michael R.
collection PubMed
description Electric fish generate and sense electric fields for navigation and communication. These signals can be energetically costly to produce and can attract electroreceptive predators. To minimize costs, some nocturnally active electric fish rapidly boost the power of their signals only at times of high social activity, either as night approaches or in response to social encounters. Here we show that the gymnotiform electric fish Sternopygus macrurus rapidly boosts signal amplitude by 40% at night and during social encounters. S. macrurus increases signal magnitude through the rapid and selective trafficking of voltage-gated sodium channels into the excitable membranes of its electrogenic cells, a process under the control of pituitary peptide hormones and intracellular second-messenger pathways. S. macrurus thus maintains a circadian rhythm in signal amplitude and adapts within minutes to environmental events by increasing signal amplitude through the rapid trafficking of ion channels, a process that directly modifies an ongoing behavior in real time.
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spelling pubmed-27415942009-09-29 Circadian and Social Cues Regulate Ion Channel Trafficking Markham, Michael R. McAnelly, M. Lynne Stoddard, Philip K. Zakon, Harold H. PLoS Biol Research Article Electric fish generate and sense electric fields for navigation and communication. These signals can be energetically costly to produce and can attract electroreceptive predators. To minimize costs, some nocturnally active electric fish rapidly boost the power of their signals only at times of high social activity, either as night approaches or in response to social encounters. Here we show that the gymnotiform electric fish Sternopygus macrurus rapidly boosts signal amplitude by 40% at night and during social encounters. S. macrurus increases signal magnitude through the rapid and selective trafficking of voltage-gated sodium channels into the excitable membranes of its electrogenic cells, a process under the control of pituitary peptide hormones and intracellular second-messenger pathways. S. macrurus thus maintains a circadian rhythm in signal amplitude and adapts within minutes to environmental events by increasing signal amplitude through the rapid trafficking of ion channels, a process that directly modifies an ongoing behavior in real time. Public Library of Science 2009-09-29 /pmc/articles/PMC2741594/ /pubmed/19787026 http://dx.doi.org/10.1371/journal.pbio.1000203 Text en Markham et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Markham, Michael R.
McAnelly, M. Lynne
Stoddard, Philip K.
Zakon, Harold H.
Circadian and Social Cues Regulate Ion Channel Trafficking
title Circadian and Social Cues Regulate Ion Channel Trafficking
title_full Circadian and Social Cues Regulate Ion Channel Trafficking
title_fullStr Circadian and Social Cues Regulate Ion Channel Trafficking
title_full_unstemmed Circadian and Social Cues Regulate Ion Channel Trafficking
title_short Circadian and Social Cues Regulate Ion Channel Trafficking
title_sort circadian and social cues regulate ion channel trafficking
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741594/
https://www.ncbi.nlm.nih.gov/pubmed/19787026
http://dx.doi.org/10.1371/journal.pbio.1000203
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