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Inactivation of aPKCλ Reveals a Context Dependent Allocation of Cell Lineages in Preimplantation Mouse Embryos

BACKGROUND: During mammalian preimplantation development, lineage divergence seems to be controlled by the interplay between asymmetric cell division (once cells are polarized) and positional information. In the mouse embryo, two distinct cell populations are first observed at the 16-cell stage and...

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Detalles Bibliográficos
Autores principales: Dard, Nicolas, Le, Tran, Maro, Bernard, Louvet-Vallée, Sophie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741596/
https://www.ncbi.nlm.nih.gov/pubmed/19768116
http://dx.doi.org/10.1371/journal.pone.0007117