Nitric Oxide Induces Cell Death by Regulating Anti-Apoptotic BCL-2 Family Members

Nitric oxide (NO) activates the intrinsic apoptotic pathway to induce cell death. However, the mechanism by which this pathway is activated in cells exposed to NO is not known. Here we report that BAX and BAK are activated by NO and that cytochrome c is released from the mitochondria. Cells deficien...

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Detalles Bibliográficos
Autores principales: Snyder, Colleen M., Shroff, Emelyn H., Liu, Jing, Chandel, Navdeep S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741604/
https://www.ncbi.nlm.nih.gov/pubmed/19768117
http://dx.doi.org/10.1371/journal.pone.0007059

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